ADVERSE DRUG REACTIONS
ADVERSE DRUG REACTION Any noxious change in the body which is suspected to be due to a drug at doses normally used in man. It may requires treatment or decrease in dose or caution in the future use of the same drug GRADING OF SEVERITY OF ADVERSE DRUG REACTIO NS : Minor : No therapy, antidote or prolongation of hospitalization is required. Moderate : Requires change in drug therapy, specific treatment or prolongs hospital stay. Severe : Potentially life-threatening, causes permanent damage or requires intensive medical treatment. Lethal : Directly or indirectly contributes to death of the patient. CLASSIFICATIONS OF ADR A (Augmented) B (Bizarre) C (Continuous) D (Delayed) E (Ending Use) F (Failure of Efficacy) Broadly Type- A (Predictable)- Based on pharmacological properties Type- B (Non-predictable) – Based on Immunological ...